Dr. Serge Gauthier


  1. Zhang, H, Therriault, J, Kang, MS, Ng, KP, Pascoal, TA, Rosa-Neto, P et al.. Cerebrospinal fluid synaptosomal-associated protein 25 is a key player in synaptic degeneration in mild cognitive impairment and Alzheimer's disease. Alzheimers Res Ther. 2018;10 (1):80. doi: 10.1186/s13195-018-0407-6. PubMed PMID:30115118 .
  2. Gauthier, S, Herrmann, N, Rosa-Neto, P. Optimal use of cholinergic drugs in Alzheimer's disease. Brain. 2018; :. doi: 10.1093/brain/awy204. PubMed PMID:30084978 .
  3. Pascoal, TA, Shin, M, Kang, MS, Chamoun, M, Chartrand, D, Mathotaarachchi, S et al.. In vivo quantification of neurofibrillary tangles with [18F]MK-6240. Alzheimers Res Ther. 2018;10 (1):74. doi: 10.1186/s13195-018-0402-y. PubMed PMID:30064520 PubMed Central PMC6069775.
  4. Jia, J, Wei, C, Chen, S, Li, F, Tang, Y, Qin, W et al.. Efficacy and safety of the compound Chinese medicine SaiLuoTong in vascular dementia: A randomized clinical trial. Alzheimers Dement (N Y). 2018;4 :108-117. doi: 10.1016/j.trci.2018.02.004. PubMed PMID:29955654 PubMed Central PMC6021260.
  5. Wu, LY, Zhan, SQ, Huang, ZY, Zhang, B, Wang, T, Liu, CF et al.. Expert Consensus on Clinical Diagnostic Criteria for Fatal Familial Insomnia. Chin. Med. J. 2018;131 (13):1613-1617. doi: 10.4103/0366-6999.235115. PubMed PMID:29941716 PubMed Central PMC6032681.
  6. Khachaturian, AS, Hayden, KM, Mielke, MM, Tang, Y, Lutz, MW, Gold, M et al.. New thinking about thinking, part two. Theoretical articles for Alzheimer's & Dementia. Alzheimers Dement. 2018;14 (6):703-706. doi: 10.1016/j.jalz.2018.05.002. PubMed PMID:29842864 .
  7. Gauthier, S, Ng, KP, Pascoal, TA, Zhang, H, Rosa-Neto, P. Targeting Alzheimer's Disease at the Right Time and the Right Place: Validation of a Personalized Approach to Diagnosis and Treatment. J. Alzheimers Dis. 2018;64 (s1):S23-S31. doi: 10.3233/JAD-179924. PubMed PMID:29504543 PubMed Central PMC6004905.
  8. Villeneuve, S, Vogel, JW, Gonneaud, J, Pichet Binette, A, Rosa-Neto, P, Gauthier, S et al.. Proximity to Parental Symptom Onset and Amyloid-β Burden in Sporadic Alzheimer Disease. JAMA Neurol. 2018;75 (5):608-619. doi: 10.1001/jamaneurol.2017.5135. PubMed PMID:29482212 PubMed Central PMC5885216.
  9. Schoemaker, D, Buss, C, Head, K, Sandman, CA, Davis, EP, Chakravarty, MM et al.. Corrigendum to "Hippocampus and amygdala volumes from magnetic resonance images in children: Assessing accuracy of FreeSurfer and FSL against manual segmentation"[NeuroImage 129 (2016) 1-14]. Neuroimage. 2018;173 :1-2. doi: 10.1016/j.neuroimage.2018.02.009. PubMed PMID:29477029 .
  10. Benedet, AL, Yu, L, Labbe, A, Mathotaarachchi, S, Pascoal, TA, Shin, M et al.. CYP2C19 variant mitigates Alzheimer disease pathophysiology in vivo and postmortem. Neurol Genet. 2018;4 (1):e216. doi: 10.1212/NXG.0000000000000216. PubMed PMID:29473050 PubMed Central PMC5820598.
  11. Mortby, ME, Black, SE, Gauthier, S, Miller, D, Porsteinsson, A, Smith, EE et al.. Dementia clinical trial implications of mild behavioral impairment. Int Psychogeriatr. 2018;30 (2):171-175. doi: 10.1017/S1041610218000042. PubMed PMID:29448970 .
  12. Therriault, J, Ng, KP, Pascoal, TA, Mathotaarachchi, S, Kang, MS, Struyfs, H et al.. Anosognosia predicts default mode network hypometabolism and clinical progression to dementia. Neurology. 2018;90 (11):e932-e939. doi: 10.1212/WNL.0000000000005120. PubMed PMID:29444971 PubMed Central PMC5858945.
  13. Jia, J, Wei, C, Chen, S, Li, F, Tang, Y, Qin, W et al.. The cost of Alzheimer's disease in China and re-estimation of costs worldwide. Alzheimers Dement. 2018;14 (4):483-491. doi: 10.1016/j.jalz.2017.12.006. PubMed PMID:29433981 .
  14. Pascoal, TA, Mathotaarachchi, S, Shin, M, Park, AY, Mohades, S, Benedet, AL et al.. Amyloid and tau signatures of brain metabolic decline in preclinical Alzheimer's disease. Eur. J. Nucl. Med. Mol. Imaging. 2018;45 (6):1021-1030. doi: 10.1007/s00259-018-3933-3. PubMed PMID:29396637 PubMed Central PMC5915512.
  15. Belleville, S, Hudon, C, Bier, N, Brodeur, C, Gilbert, B, Grenier, S et al.. MEMO+: Efficacy, Durability and Effect of Cognitive Training and Psychosocial Intervention in Individuals with Mild Cognitive Impairment. J Am Geriatr Soc. 2018;66 (4):655-663. doi: 10.1111/jgs.15192. PubMed PMID:29313875 .
  16. Sinyavskaya, L, Gauthier, S, Renoux, C, Dell'Aniello, S, Suissa, S, Brassard, P et al.. Comparative effect of statins on the risk of incident Alzheimer disease. Neurology. 2018;90 (3):e179-e187. doi: 10.1212/WNL.0000000000004818. PubMed PMID:29247073 .
  17. Li, X, Ba, M, Ng, KP, Mathotaarachchi, S, Pascoal, TA, Rosa-Neto, P et al.. Characterizing biomarker features of cognitively normal individuals with ventriculomegaly. Alzheimers Dement (Amst). 2018;10 :12-21. doi: 10.1016/j.dadm.2017.08.001. PubMed PMID:29159265 PubMed Central PMC5678356.
  18. Wilcock, GK, Gauthier, S, Frisoni, GB, Jia, J, Hardlund, JH, Moebius, HJ et al.. Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer's Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial. J. Alzheimers Dis. 2018;61 (1):435-457. doi: 10.3233/JAD-170560. PubMed PMID:29154277 PubMed Central PMC5734125.
  19. Gauthier, S, Robillard, J, de Champlain, J. Progress in transnational scientific and ethics review: Commentary on the proposal for a single North American review board for research on dementia. Alzheimers Dement. 2018;14 (1):115-116. doi: 10.1016/j.jalz.2017.10.001. PubMed PMID:29111430 .
  20. Parent, MJ, Zimmer, ER, Shin, M, Kang, MS, Fonov, VS, Mathieu, A et al.. Multimodal Imaging in Rat Model Recapitulates Alzheimer's Disease Biomarkers Abnormalities. J. Neurosci. 2017;37 (50):12263-12271. doi: 10.1523/JNEUROSCI.1346-17.2017. PubMed PMID:29097597 PubMed Central PMC5729194.
  21. Gauthier, S, Ng, KP, Pascoal, TA, Mathotaarachchi, S, Chung, CO, Benedetti, AL et al.. Author response: Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease. Neurology. 2017;89 (18):1931. doi: 10.1212/WNL.0000000000004593. PubMed PMID:29084927 .
  22. Ba, M, Li, X, Ng, KP, Pascoal, TA, Mathotaarachchi, S, Rosa-Neto, P et al.. The prevalence and biomarkers' characteristic of rapidly progressive Alzheimer's disease from the Alzheimer's Disease Neuroimaging Initiative database. Alzheimers Dement (N Y). 2017;3 (1):107-113. doi: 10.1016/j.trci.2016.12.005. PubMed PMID:29067322 PubMed Central PMC5651370.
  23. Savaskan, E, Mueller, H, Hoerr, R, von Gunten, A, Gauthier, S. Treatment effects of Ginkgo biloba extract EGb 761® on the spectrum of behavioral and psychological symptoms of dementia: meta-analysis of randomized controlled trials. Int Psychogeriatr. 2018;30 (3):285-293. doi: 10.1017/S1041610217001892. PubMed PMID:28931444 .
  24. Schoemaker, D, Poirier, J, Collins, DL, Gauthier, S, Pruessner, JC. Familiarity deficits in cognitively normal aging individuals with APOE ε4: A follow-up investigation of medial temporal lobe structural correlates. Alzheimers Dement (Amst). 2017;9 :21-24. doi: 10.1016/j.dadm.2017.05.008. PubMed PMID:28761928 PubMed Central PMC5520953.
  25. Mathotaarachchi, S, Pascoal, TA, Shin, M, Benedet, AL, Kang, MS, Beaudry, T et al.. Identifying incipient dementia individuals using machine learning and amyloid imaging. Neurobiol. Aging. 2017;59 :80-90. doi: 10.1016/j.neurobiolaging.2017.06.027. PubMed PMID:28756942 .
  26. Lajoie, I, Nugent, S, Debacker, C, Dyson, K, Tancredi, FB, Badhwar, A et al.. Application of calibrated fMRI in Alzheimer's disease. Neuroimage Clin. 2017;15 :348-358. doi: 10.1016/j.nicl.2017.05.009. PubMed PMID:28560160 PubMed Central PMC5443910.
  27. Brayet, P, Petit, D, Baril, AA, Gosselin, N, Gagnon, JF, Soucy, JP et al.. Brain perfusion during rapid-eye-movement sleep successfully identifies amnestic mild cognitive impairment. Sleep Med. 2017;34 :134-140. doi: 10.1016/j.sleep.2017.01.025. PubMed PMID:28522082 .
  28. Müller, WE, Eckert, A, Eckert, GP, Fink, H, Friedland, K, Gauthier, S et al.. Therapeutic efficacy of the Ginkgo special extract EGb761® within the framework of the mitochondrial cascade hypothesis of Alzheimer's disease. World J. Biol. Psychiatry. 2017; :1-17. doi: 10.1080/15622975.2017.1308552. PubMed PMID:28460580 .
  29. Ng, KP, Pascoal, TA, Mathotaarachchi, S, Chung, CO, Benedet, AL, Shin, M et al.. Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease. Neurology. 2017;88 (19):1814-1821. doi: 10.1212/WNL.0000000000003916. PubMed PMID:28404803 PubMed Central PMC5419982.
  30. Ng, KP, Pascoal, TA, Mathotaarachchi, S, Therriault, J, Kang, MS, Shin, M et al.. Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain. Alzheimers Res Ther. 2017;9 (1):25. doi: 10.1186/s13195-017-0253-y. PubMed PMID:28359327 PubMed Central PMC5374697.
  31. Schoemaker, D, Mascret, C, Collins, DL, Yu, E, Gauthier, S, Pruessner, JC et al.. Recollection and familiarity in aging individuals: Gaining insight into relationships with medial temporal lobe structural integrity. Hippocampus. 2017;27 (6):692-701. doi: 10.1002/hipo.22725. PubMed PMID:28281326 .
  32. Jia, J, Gauthier, S, Pallotta, S, Ji, Y, Wei, W, Xiao, S et al.. Consensus-based recommendations for the management of rapid cognitive decline due to Alzheimer's disease. Alzheimers Dement. 2017;13 (5):592-597. doi: 10.1016/j.jalz.2017.01.007. PubMed PMID:28238739 .
  33. Bergeron, D, Flynn, K, Verret, L, Poulin, S, Bouchard, RW, Bocti, C et al.. Multicenter Validation of an MMSE-MoCA Conversion Table. J Am Geriatr Soc. 2017;65 (5):1067-1072. doi: 10.1111/jgs.14779. PubMed PMID:28205215 .
  34. Zimmer, ER, Parent, MJ, Souza, DG, Leuzy, A, Lecrux, C, Kim, HI et al.. [18F]FDG PET signal is driven by astroglial glutamate transport. Nat. Neurosci. 2017;20 (3):393-395. doi: 10.1038/nn.4492. PubMed PMID:28135241 PubMed Central PMC5378483.
  35. Ismail, Z, Agüera-Ortiz, L, Brodaty, H, Cieslak, A, Cummings, J, Fischer, CE et al.. The Mild Behavioral Impairment Checklist (MBI-C): A Rating Scale for Neuropsychiatric Symptoms in Pre-Dementia Populations. J. Alzheimers Dis. 2017;56 (3):929-938. doi: 10.3233/JAD-160979. PubMed PMID:28059789 PubMed Central PMC5652315.
  36. Pascoal, TA, Mathotaarachchi, S, Shin, M, Benedet, AL, Mohades, S, Wang, S et al.. Synergistic interaction between amyloid and tau predicts the progression to dementia. Alzheimers Dement. 2017;13 (6):644-653. doi: 10.1016/j.jalz.2016.11.005. PubMed PMID:28024995 .
  37. Gauthier, S. Research update on Alzheimer's disease and introduction to the Expert Review of Neurotherapeutics special issue. Expert Rev Neurother. 2017;17 (1):1-2. doi: 10.1080/14737175.2017.1268054. PubMed PMID:27911115 .
  38. Ba, M, Kong, M, Li, X, Ng, KP, Rosa-Neto, P, Gauthier, S et al.. Is ApoE ɛ 4 a good biomarker for amyloid pathology in late onset Alzheimer's disease?. Transl Neurodegener. 2016;5 :20. doi: 10.1186/s40035-016-0067-z. PubMed PMID:27891223 PubMed Central PMC5112745.
  39. Gauthier, S, Feldman, HH, Schneider, LS, Wilcock, GK, Frisoni, GB, Hardlund, JH et al.. Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial. Lancet. 2016;388 (10062):2873-2884. doi: 10.1016/S0140-6736(16)31275-2. PubMed PMID:27863809 PubMed Central PMC5164296.
  40. Mathotaarachchi, S, Wang, S, Shin, M, Pascoal, TA, Benedet, AL, Kang, MS et al.. VoxelStats: A MATLAB Package for Multi-Modal Voxel-Wise Brain Image Analysis. Front Neuroinform. 2016;10 :20. doi: 10.3389/fninf.2016.00020. PubMed PMID:27378902 PubMed Central PMC4908129.
  41. Schoemaker, D, Poirier, J, Escobar, S, Gauthier, S, Pruessner, J. Selective familiarity deficits in otherwise cognitively intact aging individuals with genetic risk for Alzheimer's disease. Alzheimers Dement (Amst). 2016;2 :132-9. doi: 10.1016/j.dadm.2015.11.007. PubMed PMID:27239534 PubMed Central PMC4879663.
  42. Gauthier, S, Rosa-Neto, P, Kass, JS. Ethical Considerations for the Use of Next-Generation Alzheimer Drugs in Symptomatic and At-Risk Patients. Continuum (Minneap Minn). 2016;22 (2 Dementia):615-8. doi: 10.1212/CON.0000000000000306. PubMed PMID:27042911 PubMed Central PMC5390936.
  43. Schilling, LP, Zimmer, ER, Shin, M, Leuzy, A, Pascoal, TA, Benedet, AL et al.. Imaging Alzheimer's disease pathophysiology with PET. Dement Neuropsychol. ;10 (2):79-90. doi: 10.1590/S1980-5764-2016DN1002003. PubMed PMID:29213438 PubMed Central PMC5642398.
  44. Dubois, B, Hampel, H, Feldman, HH, Scheltens, P, Aisen, P, Andrieu, S et al.. Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria. Alzheimers Dement. 2016;12 (3):292-323. doi: 10.1016/j.jalz.2016.02.002. PubMed PMID:27012484 .
  45. Winblad, B, Amouyel, P, Andrieu, S, Ballard, C, Brayne, C, Brodaty, H et al.. Defeating Alzheimer's disease and other dementias: a priority for European science and society. Lancet Neurol. 2016;15 (5):455-532. doi: 10.1016/S1474-4422(16)00062-4. PubMed PMID:26987701 .
  46. Florian, H, Meier, A, Gauthier, S, Lipschitz, S, Lin, Y, Tang, Q et al.. Efficacy and Safety of ABT-126 in Subjects with Mild-to-Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors: A Randomized, Double-Blind, Placebo-Controlled Study. J. Alzheimers Dis. 2016;51 (4):1237-47. doi: 10.3233/JAD-150978. PubMed PMID:26967214 .
  47. Schoemaker, D, Buss, C, Head, K, Sandman, CA, Davis, EP, Chakravarty, MM et al.. Hippocampus and amygdala volumes from magnetic resonance images in children: Assessing accuracy of FreeSurfer and FSL against manual segmentation. Neuroimage. 2016;129 :1-14. doi: 10.1016/j.neuroimage.2016.01.038. PubMed PMID:26824403 .
  48. Gauthier, S, Albert, M, Fox, N, Goedert, M, Kivipelto, M, Mestre-Ferrandiz, J et al.. Why has therapy development for dementia failed in the last two decades?. Alzheimers Dement. 2016;12 (1):60-4. doi: 10.1016/j.jalz.2015.12.003. PubMed PMID:26710325 .
  49. Benedet, AL, Labbe, A, Lemay, P, Zimmer, ER, Pascoal, TA, Leuzy, A et al.. Epistasis analysis links immune cascades and cerebral amyloidosis. J Neuroinflammation. 2015;12 :227. doi: 10.1186/s12974-015-0436-z. PubMed PMID:26626881 PubMed Central PMC4666175.
  50. Gauthier, S, Rountree, S, Finn, B, LaPlante, B, Weber, E, Oltersdorf, T et al.. Effects of the Acetylcholine Release Agent ST101 with Donepezil in Alzheimer's Disease: A Randomized Phase 2 Study. J. Alzheimers Dis. 2015;48 (2):473-81. doi: 10.3233/JAD-150414. PubMed PMID:26402011 .
  51. Cloutier, S, Chertkow, H, Kergoat, MJ, Gauthier, S, Belleville, S. Patterns of Cognitive Decline Prior to Dementia in Persons with Mild Cognitive Impairment. J. Alzheimers Dis. 2015;47 (4):901-13. doi: 10.3233/JAD-142910. PubMed PMID:26401770 PubMed Central PMC4923749.
  52. Wajman, JR, Bertolucci, PHF, Mansur, LL, Gauthier, S. Culture as a variable in neuroscience and clinical neuropsychology: A comprehensive review. Dement Neuropsychol. ;9 (3):203-218. doi: 10.1590/1980-57642015DN93000002. PubMed PMID:29213964 PubMed Central PMC5619361.
  53. Gordon, MF, Lenderking, WR, Duhig, A, Chandler, J, Lundy, JJ, Miller, DS et al.. Development of a patient-reported outcome instrument to assess complex activities of daily living and interpersonal functioning in persons with mild cognitive impairment: The qualitative research phase. Alzheimers Dement. 2016;12 (1):75-84. doi: 10.1016/j.jalz.2015.04.008. PubMed PMID:26079412 .
  54. Gauthier, S, Proaño, JV, Jia, J, Froelich, L, Vester, JC, Doppler, E et al.. Cerebrolysin in mild-to-moderate Alzheimer's disease: a meta-analysis of randomized controlled clinical trials. Dement Geriatr Cogn Disord. 2015;39 (5-6):332-47. doi: 10.1159/000377672. PubMed PMID:25832905 .
  55. Zimmer, ER, Parent, MJ, Leuzy, A, Aliaga, A, Aliaga, A, Moquin, L et al.. Imaging in vivo glutamate fluctuations with [(11)C]ABP688: a GLT-1 challenge with ceftriaxone. J. Cereb. Blood Flow Metab. 2015;35 (7):1169-74. doi: 10.1038/jcbfm.2015.35. PubMed PMID:25806702 PubMed Central PMC4640271.
  56. Leuzy, A, Zimmer, ER, Dubois, J, Pruessner, J, Cooperman, C, Soucy, JP et al.. In vivo characterization of metabotropic glutamate receptor type 5 abnormalities in behavioral variant FTD. Brain Struct Funct. 2016;221 (3):1387-402. doi: 10.1007/s00429-014-0978-3. PubMed PMID:25596865 .
  57. Gauthier, S, Schlaefke, S. Efficacy and tolerability of Ginkgo biloba extract EGb 761® in dementia: a systematic review and meta-analysis of randomized placebo-controlled trials. Clin Interv Aging. 2014;9 :2065-77. doi: 10.2147/CIA.S72728. PubMed PMID:25506211 PubMed Central PMC4259871.
  58. Zimmer, ER, Leuzy, A, Gauthier, S, Rosa-Neto, P. Developments in Tau PET Imaging. Can J Neurol Sci. 2014;41 (5):547-53. doi: 10.1017/cjn.2014.15. PubMed PMID:25424608 .
  59. Cummings, J, Mintzer, J, Brodaty, H, Sano, M, Banerjee, S, Devanand, DP et al.. Agitation in cognitive disorders: International Psychogeriatric Association provisional consensus clinical and research definition. Int Psychogeriatr. 2015;27 (1):7-17. doi: 10.1017/S1041610214001963. PubMed PMID:25311499 PubMed Central PMC4301197.
  60. Bier, N, Grenier, S, Brodeur, C, Gauthier, S, Gilbert, B, Hudon, C et al.. Measuring the impact of cognitive and psychosocial interventions in persons with mild cognitive impairment with a randomized single-blind controlled trial: rationale and design of the MEMO+ study. Int Psychogeriatr. 2015;27 (3):511-25. doi: 10.1017/S1041610214001902. PubMed PMID:25268968 .
  61. Tourian, L Jr, Margolese, HC, Gauthier, S. Donepezil-associated mania in two patients who were using donepezil without a prescription. J Clin Psychopharmacol. 2014;34 (6):753-5. doi: 10.1097/JCP.0000000000000215. PubMed PMID:25203467 .
  62. Zimmer, ER, Parent, MJ, Cuello, AC, Gauthier, S, Rosa-Neto, P. MicroPET imaging and transgenic models: a blueprint for Alzheimer's disease clinical research. Trends Neurosci. 2014;37 (11):629-41. doi: 10.1016/j.tins.2014.07.002. PubMed PMID:25151336 .
  63. Schoemaker, D, Gauthier, S, Pruessner, JC. Recollection and familiarity in aging individuals with mild cognitive impairment and Alzheimer's disease: a literature review. Neuropsychol Rev. 2014;24 (3):313-31. doi: 10.1007/s11065-014-9265-6. PubMed PMID:25115809 .
  64. Hye, A, Riddoch-Contreras, J, Baird, AL, Ashton, NJ, Bazenet, C, Leung, R et al.. Plasma proteins predict conversion to dementia from prodromal disease. Alzheimers Dement. 2014;10 (6):799-807.e2. doi: 10.1016/j.jalz.2014.05.1749. PubMed PMID:25012867 PubMed Central PMC4240530.
  65. Zimmer, ER, Leuzy, A, Benedet, AL, Breitner, J, Gauthier, S, Rosa-Neto, P et al.. Tracking neuroinflammation in Alzheimer's disease: the role of positron emission tomography imaging. J Neuroinflammation. 2014;11 :120. doi: 10.1186/1742-2094-11-120. PubMed PMID:25005532 PubMed Central PMC4099095.
  66. Leuzy, A, Zimmer, ER, Heurling, K, Rosa-Neto, P, Gauthier, S. Use of amyloid PET across the spectrum of Alzheimer's disease: clinical utility and associated ethical issues. Amyloid. 2014;21 (3):143-8. doi: 10.3109/13506129.2014.926267. PubMed PMID:24919109 .
  67. Dubois, B, Feldman, HH, Jacova, C, Hampel, H, Molinuevo, JL, Blennow, K et al.. Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria. Lancet Neurol. 2014;13 (6):614-29. doi: 10.1016/S1474-4422(14)70090-0. PubMed PMID:24849862 .
  68. Robert, PH, König, A, Amieva, H, Andrieu, S, Bremond, F, Bullock, R et al.. Recommendations for the use of Serious Games in people with Alzheimer's Disease, related disorders and frailty. Front Aging Neurosci. 2014;6 :54. doi: 10.3389/fnagi.2014.00054. PubMed PMID:24715864 PubMed Central PMC3970032.
  69. Zimmer, ER, Leuzy, A, Bhat, V, Gauthier, S, Rosa-Neto, P. In vivo tracking of tau pathology using positron emission tomography (PET) molecular imaging in small animals. Transl Neurodegener. 2014;3 (1):6. doi: 10.1186/2047-9158-3-6. PubMed PMID:24628994 PubMed Central PMC3995516.
  70. Belleville, S, Gauthier, S, Lepage, E, Kergoat, MJ, Gilbert, B. Predicting decline in mild cognitive impairment: a prospective cognitive study. Neuropsychology. 2014;28 (4):643-52. doi: 10.1037/neu0000063. PubMed PMID:24588699 .
  71. Wu, L, Soder, RB, Schoemaker, D, Carbonnell, F, Sziklas, V, Rowley, J et al.. Resting state executive control network adaptations in amnestic mild cognitive impairment. J. Alzheimers Dis. 2014;40 (4):993-1004. doi: 10.3233/JAD-131574. PubMed PMID:24583406 .
  72. Masellis, M, Sherborn, K, Neto, P, Sadovnick, DA, Hsiung, GY, Black, SE et al.. Early-onset dementias: diagnostic and etiological considerations. Alzheimers Res Ther. 2013;5 (Suppl 1):S7. doi: 10.1186/alzrt197. PubMed PMID:24565469 PubMed Central PMC3936399.
  73. Patterson, C, Gauthier, S. Diagnosis and treatment of dementia: the fourth canadian consensus conference. Alzheimers Res Ther. 2013;5 (Suppl 1):S1. doi: 10.1186/alzrt196. PubMed PMID:24565164 PubMed Central PMC3980322.
  74. Leuzy, A, Zimmer, ER, Bhat, V, Rosa-Neto, P, Gauthier, S. Imaging biomarkers for amyloid: a new generation of probes and what lies ahead. Int Psychogeriatr. 2014;26 (5):703-7. doi: 10.1017/S1041610214000118. PubMed PMID:24524685 .
  75. Jia, J, Zhou, A, Wei, C, Jia, X, Wang, F, Li, F et al.. The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese. Alzheimers Dement. 2014;10 (4):439-447. doi: 10.1016/j.jalz.2013.09.008. PubMed PMID:24418053 .
  76. Parent, MJ, Bedard, MA, Aliaga, A, Minuzzi, L, Mechawar, N, Soucy, JP et al.. Cholinergic Depletion in Alzheimer's Disease Shown by [ (18) F]FEOBV Autoradiography. Int J Mol Imaging. 2013;2013 :205045. doi: 10.1155/2013/205045. PubMed PMID:24324884 PubMed Central PMC3844185.
  77. Anisimov, SI, Drake, RP, Gauthier, S, Meshkov, EE, Abarzhi, SI. What is certain and what is not so certain in our knowledge of Rayleigh-Taylor mixing?. Philos Trans A Math Phys Eng Sci. 2013;371 (2003):20130266. doi: 10.1098/rsta.2013.0266. PubMed PMID:24146014 .
  78. Gauthier, S, Rosa-Neto, P. Dementia: Disclosure of results to participants in dementia research. Nat Rev Neurol. 2013;9 (11):608-9. doi: 10.1038/nrneurol.2013.213. PubMed PMID:24145370 .
  79. Rowley, J, Fonov, V, Wu, O, Eskildsen, SF, Schoemaker, D, Wu, L et al.. White matter abnormalities and structural hippocampal disconnections in amnestic mild cognitive impairment and Alzheimer's disease. PLoS ONE. 2013;8 (9):e74776. doi: 10.1371/journal.pone.0074776. PubMed PMID:24086371 PubMed Central PMC3785512.
  80. Palmour, N, Vanderbyl, BL, Zimmerman, E, Gauthier, S, Racine, E. Alzheimer's disease dietary supplements in websites. HEC Forum. 2013;25 (4):361-82. doi: 10.1007/s10730-013-9217-1. PubMed PMID:23765585 .
  81. Rive, B, Gauthier, S, Costello, S, Marre, C, François, C. Synthesis and comparison of the meta-analyses evaluating the efficacy of memantine in moderate to severe stages of Alzheimer's disease. CNS Drugs. 2013;27 (7):573-82. doi: 10.1007/s40263-013-0074-x. PubMed PMID:23765561 PubMed Central PMC3709077.
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